|
 Extracorporeal
Liver Support System
Artificial extracorporeal liver support or liver dialysis detoxifies the
body when there is liver failure. For patients with hepatorenal
syndrome, this treatment has been promising. Extracorporeal liver
support is based on the same principles as hemodialysis. However,
Hemodialysis removes water-soluble toxins and does not remove albumin
bound toxins.
The clinical condition of liver failure is the buildup of toxins in the
body, which cannot be filtered out by the failing liver. Artificial
extracorporeal liver support system take the place of the liver when the
liver stops functioning, by filtering out the impurities in the blood.
The systems remove such toxins as bilirubin, bile acids, cytokines, and
medium-chain fatty acids as well as other impurities. There are
currently several artificial detoxification devices under clinical
evaluation. The Molecular Adsorbent Recirculating System or MARS. Since
1993,more than 400 patients have been treated with MARS in Europe, the
United States, and Asia. Other instruments include the Single Pass
Albumin Dialysis, SPAD, and the Prometheus system.
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